65岁以上老年早期乳腺癌手术治疗84例

  • 摘要: 目的:分析早期老年乳腺癌手术治疗的临床效果及预后, 进而探讨早期老年乳腺癌的合理术式。方法: 对武警医学院附属医院肿瘤外科1994年1月至2008年12月间收治的84例行改良根治手术和单纯全乳切除手术治疗的早期老年乳腺癌患者进行回顾性分析, 患者年龄均≥65岁, 44例行改良根治术, 40例行单纯全乳切除术。结果: 64.3% (54/84) 患者合并其他疾病, 中位随访36.5个月 (11~280个月), 改良根治手术组与单纯全乳切除手术组5年累积生存率分别为86.0%和84.7%, 无统计学差异 (P=0.786); 改良根治手术组与全乳切除手术组5年复发率分别为3.3%和7.9%, 差异无统计学意义 (P=0.565)。结论: 全乳切除术后并发症少, 恢复快, 适用于早期老年乳腺癌患者。改良根治术并未明显增加早期老年乳腺癌患者的生存率。

     

    Abstract: Surgical Therapy for Early Breast Cancer in 84 Elderly Patients Aged Over 65Zhilong JIA, Baoxia SU, Huiqun SUNCorrespondence to: Zhilong JIA, E-mail: jiazhilong@eyou.comDepartment of Oncological Surgery, The Affiliated Hospital of Medical College of Chinese People's Armed Police Force, Tianjin300162, ChinaAbstract Objective: To analyze the clinical results and prognosis of early elderly breast cancer patients after surgery and to ex-plore the rational treatment. Methods: Between January 1994 and December 2008, 84 early elderly breast cancer patients aged ≥ 65years were treated with surgery. Forty-four patients underwent modified radical mastectomy and 40 underwent simple mastectomy. Re-sults: Fifty-four ( 64.3% ) patients had comorbidities, including coronary heart disease, hypertension, diabetes, and so on. After a medi-an follow up of 36.5 months ( 11 to 280 months ), the five-year cumulative survival rate in the breast-modified radical mastectomygroup and mastectomy group were 86.0% and 84.7%, respectively ( P = 0.786 ). The five-year recurrence rates were 3.3% and 7.9%, re-spectively ( P = 0.565 ). Conclusion: Simple mastectomy is suitable for the treatment of early elderly breast cancer patients due to itslower complication and recurrence rates. Early elderly women with breast cancer may be safely treated using simple mastectomy. Modi-fied radical mastectomy does not significantly increase the overall survival.Keywords Elderly; Breast cancer; Modified radical mastectomy; Mastectomy

     

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